Pure Appl. Chem., 2012, Vol. 84, No. 6, pp. 1341-1351
http://dx.doi.org/10.1351/PAC-CON-11-08-22
Published online 2012-02-08
Synthesis and structure–activity studies of simplified analogues of aplysiatoxin with antiproliferative activity like bryostatin-1
Kazuhiro Irie1,2*, Masayuki Kikumori1, Hiroaki Kamachi1, Keisuke Tanaka1, Akira Murakami1, Ryo C. Yanagita3,1, Harukuni Tokuda4, Nobutaka Suzuki4, Hiroshi Nagai5, Kiyotake Suenaga6 and Yu Nakagawa1,7
1 Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan
2 Research Unit for Physiological Chemistry, the Center for the Promotion of Interdisciplinary Education and Research, Kyoto University, Kyoto 606-8502, Japan
3 Department of Applied Biological Science, Faculty of Agriculture, Kagawa University, Kagawa 761-0195, Japan
4 Department of Complementary and Alternative Medicine, Clinical R&D, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8640, Japan
5 Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan
6 Faculty of Science and Technology, Keio University, Yokohama 223-8522, Japan
7 Synthetic Cellular Chemistry Laboratory, Advanced Science Institute, RIKEN, Saitama 351‑0198, Japan
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